Everton manager Roberto Martinez will bring in several squad players, with Darron Gibson, Aiden McGeady and Steven Naismith all in line for a start.
Phil Jagielka will also make a return from his knee injury after sitting on the bench for the last two matches.
Daggers boss John Still is without Matt Richards and Zavon Hines, due to knee and Achilles injuries respectively.
But Oliver Muldoon, the club’s new loan signing from Charlton, is in line for his debut.
Editor’s Note: Dagenham & Redbridge secured their big day out at Goodison Park after being taken to a replay by National League South side Whitehawk, they will be hoping to pull of a similar giantkilling feat when they go up against Everton.
Everton will be looking for their second cup win in the space of 3 days after getting the better of Manchester City in the Capital One Cup on Wednesday. Roberto Martinez will use this game to rotate his squad and allow the fringe players to get some game time.
John Still has returned to the Victoria Ground after being sacked by Luton and has a battle to make sure Dag & Red don’t drop down to the National League next season. Today though it’s not about survival it’s about making the most of the big occasion. He’ll have to make sure his side don’t get too overawed by the opposition and try to make the game competitive.
I can’t see Everton having too many issues this afternoon and think there will be nothing other than a home win this afternoon.